a tool for identifying drug-targetable redox-active disulphides

Interferon-activable protein 202

Intramolecular

Cysteine 383 and cysteine 385

A redox-regulated disulphide may form within Interferon-activable protein 202 between cysteines 383 and 385.

Details

Redox score ?

72

PDB code

Structure name

crystal structure of the tetrameric p202 hin2

Structure deposition date

2013-06-11

Thiol separation (Å)

4

Half-sphere exposure sum ?

77

Minimum pK_a ?

7

% buried

96

Peptide accession

Residue number A

383

Residue number B

385

Peptide name

Interferon-activable protein 202

Ligandability

Cysteine 383 of Interferon-activable protein 202

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 385 of Interferon-activable protein 202

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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